The scientist is not a person who gives the right answers, he’s one who asks the right questions.
Claude Lévi-Strauss

The most exciting phrase to hear in science, the one that heralds new discoveries, is not ‘Eureka!’ (I found it!) but ‘That’s funny…’
Isaac Asimov

In theory, there is no difference between theory and practice. But, in practice, there is.
Jan L. A. van de Snepscheut

Contrary to what Asimov says, the most exciting phrase in science, the one that heralds new discoveries, is not ‘Eureka!’ or ‘That’s funny…,’ it’s ‘Your research grant has been approved.’
John Alejandro King

A theory is something nobody believes, except the person who made it. An experiment is something everybody believes, except the person who made it.
Attributed to Albert Einstein

The purpose of models is not to fit the data but to sharpen the questions.
Samuel Karlin

Research is what I’m doing when I don’t know what I’m doing.
Wernher von Braun

Nothing is more practical than a good theory.
Kurt Lewin

Just as there are odors that dogs can smell and we cannot, as well as sounds that dogs can hear and we cannot, so too there are wavelengths of light we cannot see and flavors we cannot taste. Why then, given our brains wired the way they are, does the remark, “Perhaps there are thoughts we cannot think,” surprise you?
Richard Hamming

An expert is a person who has made all the mistakes that can be made in a very narrow field.
Niels Bohr

An expert is one who knows more and more about less and less until he knows absolutely everything about nothing.
Nicholas Butler

Essentially, all models are wrong, but some are useful.
George E. P. Box

Theory is when you know everything but nothing works. Praxis is when everything works but no one knows why. In our lab, theory and praxis are combined: nothing works and no one know why.

Pavel Vasil’evich liked only his own articles, while articles written by others, which he was supposed to read or listen to, always felt to him like a cannon muzzle directed straight at his face.
Anton P. Chekhov

The great tragedy of Science — the slaying of a beautiful hypothesis by an ugly fact.
Thomas Henry Huxley

So, in the face of overwhelming odds, I’m left with only one option, I’m gonna have to science the shit out of this.
Mark Watney

The fact that we live at the bottom of a deep gravity well, on the surface of a gas covered planet going around a nuclear fireball 90 million miles away and think this to be normal is obviously some indication of how skewed our perspective tends to be.
Douglas Adams, The Salmon of Doubt: Hitchhiking the Galaxy One Last Time

You’d be amazed how much research you can get done when you have no life whatsoever.
Ernest Cline, Ready Player One

When you have eliminated all which is impossible, then whatever remains, however improbable, must be the truth.
Sherlock Holmes

With four parameters I can fit an elephant, and with five I can make him wiggle his trunk.
John von Neumann

The purpose of computing is insight, not numbers.
Richard Hamming

The most important thing about an equation is all the quantities that don’t appear in it; once we know what the essentials are, figuring out how they depend on each other is often the easier part.
Pedro Domingos, The Master Algorithm

Thermodynamics is easy – I’ve learned it many times.
Harvey S. Leff

Far better an approximate answer to the right question, which is often vague, than an exact answer to the wrong question, which can always be made precise.
John Tukey, The future of data analysis

An article about computational result is advertising, not scholarship. The actual scholarship is the full software environment, code and data, that produced the result.
Buckheit and Donoho (1995)

Brain beats muscle as surely as paper beats rock.
Jonathan Safran Foer, Here I Am

”Forty-two!” yelled Loonquawl. ”Is that all you’ve got to show for seven and a half million years’ work?”
”I checked it very thoroughly,” said the computer, ”and that quite definitely is the answer. I think the problem, to be quite honest with you, is that you’ve never actually known what the question is.”
”But it was the Great Question! The Ultimate Question of Life, the Universe and Everything!” howled Loonquawl.
”Yes,” said Deep Thought with the air of one who suffers fools gladly, ”but what actually is it?”
A slow stupefied silence crept over the men as they stared at the computer and then at each other.
”Well, you know, it’s just Everything … Everything … ” offered Phouchg weakly.
”Exactly!” said Deep Thought. ”So once you do know what the question actually is, you’ll know what the answer means.”
Douglas Adams, The Hitchiker’s Guide to the Galaxy

Computers are useless. They can only give you answers.
Pablo Picasso

The true and only goal of science is to reveal unity rather than mechanism.
Henri Poincaré

One of the principal objects of theoretical research is to find the point of view from which the subject appears in the greatest simplicity.
Josiah Willard Gibbs

The future is already here — it’s just not very evenly distributed.
William Gibson

True science teaches, above all, to doubt and to be ignorant.
Miguel de Unamuno

If you are the smartest person in the room, then you are in the wrong room.

Dividing one number by another is mere computation; knowing what to divide by what is mathematics.
Jordan Ellenberg, How Not to Be Wrong: The Power of Mathematical Thinking

I’ve been in this argument a thousand times. Won them all and convinced nobody.
Amos Tversky, on the hot hand fallacy

Mathematics is the extension of common sense by other means.
Jordan Ellenberg, How Not to Be Wrong: The Power of Mathematical Thinking

If I had more time, I would have written a shorter letter.
Blaise Pascal

I am going to give what I will call an elementary demonstration. But elementary does not mean easy to understand. Elementary means that very little is required to know ahead of time in order to understand it, except to have an infinite amount of intelligence. There may be a large number of steps that hard to follow, but to each does not require already knowing the calculus or Fourier transforms.
Richard P. Feynman

In this section a mathematical model of the growing embryo will be described. This model will be a simplification and an idealization, and consequently a falsification. It is to be hoped that the features retained for discussion are those of greatest importance in the present state of knowledge.
Alan Turing, The Chemical Basis of Morphogenesis

Problems worthy of attack prove their worth by hitting back.
Piet Hein

Art is solving problems that cannot be formulated before they have been solved. The shaping of the question is part of the answer.
Piet Hein